Anti-Human CTLA4 Recombinant Antibody (TAB-067)

Name: Anti-Human CTLA4 Recombinant Antibody (TAB-067)
SKU: TAB-067
Rating: 5 (1 reviews)

CAT#: TAB-067

Recombinant monoclonal antibody to CTLA4. It is a drug used for the treatment of melanoma, a type of skin cancer. It is a U.S. Food and Drug Administration (FDA) approved human monoclonal antibody, and works by activating the immune system by targeting CTLA-4.
Cytotoxic T lymphocytes (CTLs) can recognize and destroy cancer cells. However, there is also an inhibitory mechanism that interrupts this destruction. It turns off this inhibitory mechanism and allows CTLs to continue to destroy cancer cells.

Tested Data Gene Expression

Figure 1 Anti-CTLA4 Antibody (TAB-067) in WB

Western blot analysis of TAB-067 was performed with CTLA-4 Protein, Human, Recombinant (His Tag).

TAB-067 incubation concentration: 2ng/μL.
The secondary antibody: HRP-Anti-Human IgG (H+L)
Lane 1: Reducing Antigen (0.1μg)
Lane 2: Reducing Antigen (0.3μg)
Lane 3: Reducing Antigen (0.6μg)

ELISA

Figure 2 Anti-CTLA4 Antibody (TAB-067) in ELISA

ELISA analysis of TAB-067 was performed by coating with CTLA-4 Protein, Human, Recombinant (His Tag).

The secondary antibody: HRP-Anti-Human IgG (H+L)

❮

❯

RNA Expression Figure 1 RNA cell line category: Cell line enhanced (Karpas-707, SK-MEL-30, U-266/70, U-266/84)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163599-CTLA4

❮

❯

Specifications

Immunogen
The details of the immunogen for this antibody are not available.

Host Species
Human

Derivation
Human

Type
IgG1 - kappa

Specificity
Tested positive against native human antigen.

Species Reactivity
Human

Applications
WB, FuncS, IF, Neut, ELISA, FC, IP, IHC

MW
148,634.914 g/mol

Related Disease
Melanoma, metastatic

Product Property

Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

Storage
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

Applications

Application Notes
The CTLA4 antibody has been reported in applications of WB, FuncS, IF, Neut, ELISA, FC, IP, IHC.

Target

Alternative Names
Ipilimumab;yervoy;477202-00-9;MDX-010;MDX-101;Yervoy;MDX-010;MDX-101;CTLA4;cytotoxic T-lymphocyte-associated protein 4;celiac disease 3 , CELIAC3;cytotoxic T-lymphocyte protein 4;CD;CD28;CD152;GSE;ICOS;CD152 isoform;celiac disease 3;cytotoxic T-lymphocyte

Gene ID
1493

UniProt ID
P16410

REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS

Inquiry

Navs

Customer Review

There are currently no Customer reviews or questions for TAB-067. Click the button above to contact us or submit your feedback about this product.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Related Diseases

Rheumatoid Arthritis

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-067.pdf

MSDS

MSDS - TAB-067.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunofluorescence (IF)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

See other products for "CTLA4"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
TAB-206	Anti-Human CTLA4 Recombinant Antibody (Ticilimumab (Tremelimumab))	WB, IF, IP, Neut, FuncS, ELISA, FC	IgG2

CAT	Product Name	Application
AGTO-G015E	Anti-CTLA4 immunotoxin (scFv)-PE	Cytotoxicity assay, Function study
AGTO-G015S	Anti-CTLA4 immunotoxin (scFv)-Sap	Cytotoxicity assay, Function study
AGTO-G015M	Anti-CTLA4 immunotoxin (scFv)-Mel	Cytotoxicity assay, Function study

CAT	Product Name	Application	Type
TAB-195CL	Mouse Anti-CTLA4 Recombinant Antibody (TAB-195CL)	ELISA	Mouse IgG

CAT	Product Name	Application	Type
TAB-083MZ	Anti-Human CTLA4 Recombinant Antibody (TGN2122.H)	ELISA, FC	Humanized antibody
TAB-084MZ	Anti-Human CTLA4 Recombinant Antibody (TGN2422.H)	ELISA, FC	Humanized antibody
TAB-088MZ	Human Anti-CTLA4 Recombinant Antibody (TAB-088MZ)	ELISA	Human IgG
TAB-091MZ	Human Anti-CTLA4 Recombinant Antibody (TAB-091MZ)	ELISA	Human IgG1
TAB-092MZ	Human Anti-CTLA4 Recombinant Antibody (TAB-092MZ)	ELISA	Human IgG1

CAT	Product Name	Application	Type
TAB-085MZ	Anti-Human CTLA4 Recombinant Antibody (TGN2122.C)	ELISA, FC	Chimeric antibody (mouse/human)
TAB-085MZ-S(P)	Anti-Human CTLA4 Recombinant Antibody scFv Fragment (TGN2122.C)	ELISA, FC	Chimeric antibody (mouse/human)
TAB-086MZ-S(P)	Anti-Human CTLA4 Recombinant Antibody scFv Fragment (TGN2422.C)	ELISA, FC	Chimeric antibody (mouse/human)
TAB-085MZ-F(E)	Anti-Human CTLA4 Recombinant Antibody Fab Fragment (TGN2122.C)	ELISA, FC	Chimeric antibody (mouse/human)
TAB-086MZ-F(E)	Anti-Human CTLA4 Recombinant Antibody Fab Fragment (TGN2422.C)	ELISA, FC	Chimeric antibody (mouse/human)

CAT	Product Name	Application	Type
TAB-087MZ-S(P)	Mouse Anti-CTLA4 Recombinant Antibody; scFv Fragment (TAB-087MZ-S(P))	ELISA	Mouse scFv
TAB-089MZ-S(P)	Mouse Anti-CTLA4 Recombinant Antibody; scFv Fragment (TAB-089MZ-S(P))	ELISA	Mouse scFv
TAB-090MZ-S(P)	Mouse Anti-CTLA4 Recombinant Antibody; scFv Fragment (TAB-090MZ-S(P))	ELISA	Mouse scFv
TAB-093MZ-S(P)	Anti-Human CTLA4 Recombinant Antibody scFv Fragment (Mu-26B)	ELISA
TAB-087MZ-F(E)	Mouse Anti-CTLA4 Recombinant Antibody; Fab Fragment (TAB-087MZ-F(E))	ELISA	Mouse Fab

CAT	Product Name	Application	Type
NEUT-567CQ	Mouse Anti-CTLA4 Recombinant Antibody (NEUT-567CQ)	FC, FuncS, Neut, IP, WB	Mouse IgG2a, κ
NEUT-569CQ	Mouse Anti-CTLA4 Recombinant Antibody (clone AS32)	WB, Neut	Mouse IgG1
NEUT-570CQ	Human Anti-CTLA4 Recombinant Antibody (clone YC030)	Neut	Human IgG1, κ
NEUT-572CQ	Hamster Anti-Ctla4 Recombinant Antibody (clone UC10-4B9)	FC, Block, ELISA, IP	Hamster IgG
NEUT-573CQ	Rat Anti-Ctla4 Recombinant Antibody (clone 63828)	WB, FC, Neut	Rat IgG2a

CAT	Product Name	Application	Type
NEUT-568CQ	Mouse Anti-CTLA4 Recombinant Antibody (clone L3D10)	FC, Block	Mouse IgG1, κ
NEUT-571CQ	Mouse Anti-CTLA4 Recombinant Antibody (clone BN13)	Block, FC	Mouse IgG2a
NEUT-577CQ	Hamster Anti-Ctla4 Recombinant Antibody (clone MAB0835)	Block, FC	Hamster IgG
NEUT-578CQ	Hamster Anti-Ctla4 Recombinant Antibody (NEUT-578CQ)	Block	Hamster IgG
NEUT-579CQ	Hamster Anti-Ctla4 Recombinant Antibody (clone 9H10)	FC, Block	Hamster IgG

CAT	Product Name	Application	Type
MOR-0855	Hi-Affi™ Rabbit Anti-CTLA4 Recombinant Antibody (clone DS855AB)	WB	Rabbit IgG

CAT	Product Name	Application	Type
HPAB-N0343-YC-S(P)	Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-N0343-YC-S(P))	FC, ELISA	Human scFv
HPAB-0752LY-S(P)	Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-0752LY-S(P))	FuncS, ELISA	Human scFv
HPAB-0753LY-S(P)	Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-0753LY-S(P))	FuncS, ELISA	Human scFv
HPAB-0754LY-S(P)	Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-0754LY-S(P))	FuncS, ELISA	Human scFv
HPAB-0755LY-S(P)	Human Anti-CTLA4 Recombinant Antibody; scFv Fragment (HPAB-0755LY-S(P))	FuncS, ELISA	Human scFv

CAT	Product Name	Application	Type
HPAB-0749LY	Human Anti-CTLA4 Recombinant Antibody (HPAB-0749LY)	FuncS, ELISA	Human IgG
HPAB-0750LY	Human Anti-CTLA4 Recombinant Antibody (HPAB-0750LY)	FuncS, ELISA	Human IgG
HPAB-0751LY	Human Anti-CTLA4 Recombinant Antibody (HPAB-0751LY)	FuncS, ELISA	Human IgG
HPAB-0752LY	Human Anti-CTLA4 Recombinant Antibody (HPAB-0752LY)	FuncS, ELISA	Human IgG
HPAB-0753LY	Human Anti-CTLA4 Recombinant Antibody (HPAB-0753LY)	FuncS, ELISA	Human IgG

CAT	Product Name	Application	Type
HPAB-0749LY-F(E)	Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0749LY-F(E))	FuncS, ELISA	Human Fab
HPAB-0750LY-F(E)	Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0750LY-F(E))	FuncS, ELISA	Human Fab
HPAB-0751LY-F(E)	Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0751LY-F(E))	FuncS, ELISA	Human Fab
HPAB-0752LY-F(E)	Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0752LY-F(E))	FuncS, ELISA	Human Fab
HPAB-0753LY-F(E)	Human Anti-CTLA4 Recombinant Antibody; Fab Fragment (HPAB-0753LY-F(E))	FuncS, ELISA	Human Fab

CAT	Product Name	Application	Type
AFC-TAB-067	Afuco™ Anti-CTLA4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-067)	FuncS, IF, Neut, ELISA, FC	ADCC enhanced antibody
AFC-TAB-206	Afuco™ Anti-CTLA4 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-206)	IF, IP, Neut, FuncS, ELISA	ADCC enhanced antibody

CAT	Product Name	Application	Type
HPAB-AP863-YC	Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP863-YC)	ELISA, Block	Camel VHH
HPAB-AP864-YC	Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP864-YC)	ELISA, Block	Camel VHH
HPAB-AP865-YC	Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP865-YC)	ELISA, Block	Camel VHH
HPAB-AP866-YC	Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP866-YC)	ELISA, Block	Camel VHH
HPAB-AP867-YC	Camelid Anti-CTLA4 Recombinant Antibody; VHH Fragment (HPAB-AP867-YC)	ELISA, Block	Camel VHH

CAT	Product Name	Application	Type
VS-0724-XY22	Mouse Anti-CTLA4 Agonistic Antibody (VS-0724-XY22)	WB, Agonistic assays	Mouse IgG1

CAT	Product Name	Application	Type
VS-0424-XY73	AbPlus™ Anti-CTLA4 Magnetic Beads (14D3)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-0225-XY92	CytoStream™ Mouse Anti-CTLA4 Recombinant Antibody (clone BNI3)	FC	Mouse IgG2a, kappa
VS-0225-XY93	CytoStream™ Armenian Hamster Anti-CTLA4 Recombinant Antibody (clone UC10-4F10-11)	FC, IP	Armenian Hamster IgG1, kappa

CAT	Product Name	Application	Type
VS-0325-FY63	Human Anti-CTLA4 (clone JMW-3B3) scFv-Fc Chimera	ELISA	Human IgG1, scFv-Fc

CAT	Product Name	Application	Type
VS-0425-YC558	Recombinant Anti-CTLA4 Vesicular Antibody, EV Displayed (VS-0425-YC558)	ELISA, FC, SPR, Neut, Cell-uptake

CAT	Product Name	Application	Type
VS-0525-XY1763	Anti-CTLA4 Immunohistochemistry Kit	IHC
VS-0525-XY1764	Anti-Mouse CTLA4 Immunohistochemistry Kit	IHC

Specific Inquiry

Size:

Conjugation:

Endotoxin:

Purity:

Formats:

Isotype Switching:

Fc Engineering:

Modalities:

Add to compare

Request
Custom Production

See Our Custom Production in Action

Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE

Download the full case study

Popular Products

Figure 2 Anti-TGF beta 2 Antibody (TAB-100) in HPLC

Anti-Human TGF beta 2 Recombinant Antibody (TAB-100) (CAT# TAB-100)
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC

Figure 2 Anti-SLAMF7 Recombinant Antibody (TAB-743) in WB

Anti-SLAMF7 Recombinant Antibody (Elotuzumab) (CAT# TAB-743)
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC

Figure 2 Anti-IL22 Recombinant Antibody (TAB-748) in HPLC

Anti-IL22 Recombinant Antibody (TAB-748) (CAT# TAB-748)
Application: WB, IP, IF, FuncS, FC, Neut, ELISA

Figure 2 Anti-Human CD30 Recombinant Antibody (TAB-144) in ELISA

Anti-Human CD30 Recombinant Antibody (Iratumumab) (CAT# TAB-144)
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC

Figure 5 Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) in ELISA

Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) (CAT# TAB-709)
Application: IF, IP, Neut, FuncS, ELISA, FC, WB

Figure 2 Anti-Human CD18 Recombinant Antibody, hIgG1 (TAB-154-F(E)) in HPLC

Anti-Human CD18 Recombinant Antibody F(ab')₂ Fragment (TAB-154-F(E)) (CAT# TAB-154-F(E))
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC

Figure 3 Anti-Human SPP1 Antibody (TAB-582CL) in DB

Anti-Human SPP1 Recombinant Antibody (ASK8007) (CAT# TAB-582CL)
Application:

Figure 3 Human Anti-HIV-1 gp41 Recombinant Antibody (clone 4E10) (PABL-192) in Dot Blot

Human Anti-HIV-1 gp41 Recombinant Antibody (clone 4E10) (CAT# PABL-192)
Application: WB, Neut, FuncS

Figure 3 Mouse Anti-VEGF Recombinant Antibody (PABW-130) in ELISA

Mouse Anti-VEGF Recombinant Antibody (clone A4.6.1) (CAT# PABW-130)
Application: Neut, ELISA, Inhib, ICC, WB

Figure 1 Anti-CD3 Antibody (TAB-0416CL) Induced PBMCs Proliferation

Mouse Anti-CD3 Recombinant Antibody (TAB-0416CL) (CAT# TAB-0416CL)
Application: FC, IB, ELISA

Figure 2 Anti-CD5 Antibody (53-7.3) Fab Fragment (NEUT-392CQ-Fab) in ELISA

Rat Anti-CD5 Recombinant Antibody (clone 53-7.3) (CAT# NEUT-392CQ)
Application: FC, IHC-Fr, IP, ELISA, Block

Figure 2 Mouse Anti-Id Recombinant Antibody (FAMAB-0073-CN) in HPLC

Mouse Anti-Id Recombinant Antibody (clone 1A7) (CAT# FAMAB-0073-CN)
Application: ELISA, FC, RIA

Figure 6 Recombinant Mouse Anti-EBV gH/gL Antibody (CL59) (PABC-523) in Dot Blot

Mouse Anti-EBV gH/gL Recombinant Antibody (clone CL59) (CAT# PABC-523)
Application: ELISA, FC, Neut, Inhib

Figure 5 Anti-Human CDH17 Recombinant Antibody (HPAB-2061LY) in ELISA

Human Anti-CDH17 Recombinant Antibody (clone D2101) (CAT# HPAB-2061LY)
Application: ELISA

Figure 2 Anti-DOTA Antibody (HPAB-1251WJ) in HPLC

Mouse Anti-DOTA Recombinant Antibody (HPAB-1251WJ) (CAT# HPAB-1251WJ)
Application: ELISA, Inhib

Figure 3 Mouse Anti-Fibrin β chain Antibody (MOB-195YJL) in DB

Mouse Anti-Fibrin β chain Recombinant Antibody (MOB-195YJL) (CAT# MOB-195YJL)
Application: ELISA

Figure 11 Mouse Anti-ERBB2 Antibody in IHC

Mouse Anti-ERBB2 Recombinant Antibody (clone ABT-Her2) (CAT# ZG-0100C)
Application: IHC-P, IF

Figure 3 Mouse Anti-SOX9 Antibody (clone ABT-SOX9) in WB

Mouse Anti-SOX9 Recombinant Antibody (clone ABT-SOX9) (CAT# ZG-0104C)
Application: IHC-P, IF

Figure 4 Mouse Anti-ATG5 Recombinant Antibody (clone 3C7) in WB

Mouse Anti-ATG5 Recombinant Antibody (clone 3C7) (CAT# ZG-0038J)
Application: IF, ICC, WB, IHC-P, IP

Figure 2 Mouse Anti-Modified citrulline Antibody (ZG-453C) in WB

Mouse Anti-Modified citrulline Recombinant Antibody (clone 4CS) (CAT# ZG-453C)
Application: ELISA, WB

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.